Abstract
Vitamin E is the generic descriptor for all tocopherol and tocotrienol derivatives exhibiting the biological activity of α-tocopherol. It has a fundamental role in all cells as a biological antioxidant protecting against lipid peroxidation by scavenging of free radicals. It functions as a modulator of cell signaling and gene expression, has antiinflammatory effects, and functions in enzyme regulation and gene expression. The vitamers E are fat-soluble and require micellar solubilization for absorption. The primary dietary sources of vitamin E are vegetable oils, seeds, and cereal grains. Frank vitamin E deficiency is not common in humans and is manifest clinically as hemolytic anemia.
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