Abstract
This chapter focuses on novel findings obtained from clinical studies and mouse models that demonstrate the importance of intact gastric acidification for calcium homeostasis and skeletal integrity. Given the high prevalence of hypochlorhydria in the aged population, it is indeed important to address the question of whether an increased gastric pH is a relevant risk factor for osteoporosis, and, if so, if these individuals would profit from specific calcium supplementation. Moreover, the following discussion of the current knowledge regarding these questions provides another example for the critical importance of a complete osteologic patient assessment and for the requirement of in vivo models to understand bone as an integral part of the organism.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
