Abstract

Chromatographic analytical methods for the analysis of organic chemicals are widely available. The majority of these methods have common elements, such as dissolving the analyte in organic solvent, removing the interfering coextractives by column chromatography and then injecting the purified extract onto a gas chromatograph coupled to a detector. This review attempts to summarize the best practices, provides guidelines and some procedures to extract, isolate, concentrate, separate, identify, and quantify organic compounds by chromatography. It also includes some information on the collection, preparation, and storage of samples, as well as specific quality control and reporting criteria. Performance-based processes are described so that individual laboratories can adapt the methods best suited to their situations.

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