Abstract

Nanosuspensions are very fine colloid, biphasic, dispersed solid drug particles in an aqueous medium having size in range of 10–1000nm without any matrix material that are stabilized by surfactants and polymers. They are prepared through different methods exploiting the principles of particle size reduction. They are characterized for drug particle size, size distribution, dissolution rate, saturation, and in vivo performance. Nanosuspensions have been effective in delivering the poor water-soluble drugs to target tissues with their ultimate enhanced bioavailability and better therapeutic outcomes. Nanosuspensions are quite able to target the drugs to various vital organs by virtue of their submicron size or surface modifications. They are extensively used for delivering anticancer agents specifically to tumors, thus avoiding their toxic effects on healthy tissues.

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