Abstract

The drug molecules, genes, DNA, RNA, pesticides, nutraceuticals, and inhibitors agent were incorporated into nanocontainer or conjugated with nanostructures for the various applications. It can overcome certain characteristic disadvantages of the free components, such as poor water solubility, high dosage, and short half-life in the treatment. In this chapter, we discuss drug loading and releasing mechanisms of active components in the nanocontainer system. Drug loading is followed by two major mechanisms—chemical interactions and physical interactions, with various bonds, including covalent bond, hydrogen bond, electrostatic interaction, hydrophobic interaction, and van der Waals interactions. In the second part of this chapter, we investigate the releasing mechanism of the nanocontainer and consider the types of their releasing system and influences of the key factors.

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