Abstract
Increasing demand for high sensitivity, high selectivity, and rapid detection brings a lot of opportunities in sensor search. Although existing sensing technologies are capable of accurate and specific biomolecule determination, they are considered inadequate given inherent challenges in low concentration and rapid detection. In the last decade, electronic sensors based on field-effect transistors (FETs) have been widely studied due to their extremely high sensitivity, rapid response, and simple test procedure. Among them, graphene-based FET sensors have been demonstrated for the detection of a wide range of biomolecules and present tremendous potential in biomedical applications. The scope and focus of this chapter is graphene-based FET sensors for biomolecule detection including protein, DNA, living cell, and bacterium. The advantages and recent progress on graphene FET sensors for biomolecule detection will be introduced. An outlook for challenges and future directions of graphene FET sensors in biomolecule sensing is also provided.
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