Abstract

The consumption of a diet rich in fruits includes many health benefits, and some of its bioactive compounds exert antioxidant properties. Inflammatory bowel disease (IBD) affects the gastrointestinal tract in a chronic process, and its etiopathogenesis is complex, involving many factors. Considering the beneficial properties of fruits, the purpose of this chapter is to provide a description and discussion from several experimental studies that investigated their effects on IBD. Studies concerning the properties of grape, apple, mango, berry fruits, and pomegranate were addressed. The underlying mechanisms were antiinflammatory, antioxidant activity, and prevention of apoptosis. In addition, there was an important contribution to the modulation of intestinal microbiota and an improvement of epithelial barrier function. All these mechanisms are closely related to bioactive compounds present in these fruits. The possibility of combining fruits products with commonly used drugs to treat IBDs is a promising alternative of therapeutic option for these patients.

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