Abstract
Kampo and/or traditional medicines have been used to treat humans as a whole, but not to treat specific pathogenic targets, because the strategy of treating disease is focused on the improvement of the inherent human potential against disease. In addition to clinically defined endpoint diseases, the so-called “mibyou” condition, alternatively the subhealthy condition, is a target of Kampo medicines. The mibyou, which is defined in traditional Oriental medicine as the condition or state located between health and disease, but closer to disease, is not pathologically fully defined, but oxidative stress might be one of its indications, because oxidative stress is a condition that leads to many diagnosed diseases. Herbal medicines, including Kampo medicines, usually comprised several herbal components that contain various types of antioxidants, such as polyphenolics, and thus are frequently applied to treat the mibyou condition.
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