Abstract
Barrett's esophagus is an acquired condition of metaplasia in which normal squamous epithelium is replaced with metaplastic intestinal columnar epithelium. It is a precursor of adenocarcinoma. Chronic gastroesophageal reflux is the main risk factor. The diagnosis requires endoscopic visualization and biopsy. Treatment depends on the grade of histologic dysplasia and the length of the metaplastic segment. Management options could include proton pump inhibition, anti-reflux surgery, endoscopic mucosal resection, endoscopic radiofrequency ablation, and esophagectomy.
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