Abstract
For the past few decades, drug delivery systems have become one of the main research fields of the science community in advanced biomedicine. The concept of nanodrugs and the manufacturing of drug delivery systems itself have met impressive heights. In practice, various types of nanodrug systems are provided, most of them with the drugs encapsulated in variously shaped nanocarries, such as dendrimers, liposomes, micelles, and polymer nanoparticles. Nanodrug systems feature a series of pharmacokinetic advantages, such as targeted drug delivery, superior metabolic stability, and membrane permeability, enhanced bioavailability, and prolonged effects. This novel promising therapeutic approach exhibits a high degree of versatility due to the behavioral variability governed by physicochemical properties, such as size, surface charge, and hydrophilic/hydrophobic character. The purpose of this chapter was to offer a thorough report of the recent progresses and degree of toxicity that could be generated by a number of new medical therapies, with a strong impact on medicine, namely “therapeutic devices” based on nanoparticles.
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