Abstract
X-ray crystallography is used to examine a sample that is in the crystalline state. Crystals of many proteins and other biomoleculars have been obtained and analyzed in the X-ray beam. A few macromolecular crystals are discussed in the chapter through various figures. It gives evidence that solution and crystal structures are similar and outlines the process of growing protein crystals. From basic procedure, growing derivate crystals, to finding optimal conditions for crystal growth, the chapter discusses it all. In addition, it presents tests to judge crystal quality. The process of mounting crystals for data collection is discussed too. The chapter concludes by summarizing a few benefits of crystallography. It offers better diffraction, reduction of radiation damage to the crystal, reduction of X-ray scattering from water, possibility of safe storage, transport, and reuse of crystals.
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