Abstract

From a patient compliance perspective, solid oral dosages have a clear and acceptable precedence and, therefore, tend to be the favored route of administration. Tablets and capsules are widely manufactured and prescribed, and provide a number of advantages over other dosage forms such as ease of storage, portability, straightforward administration, and accuracy in dosing. Numerous aspects (such as the selecting the right type of dosage form, excipients, compatibility of the drug with the excipient, composition, manufacturability, impact on bioavailability, etc.) need to be considered while developing the drug product's formulation. Quite simply, formulation development can be considered an amalgamation and incorporation of core concepts in chemistry, pharmacokinetics, engineering technologies, and manufacturing practices to produce a product that is bioavailable, stable, manufacturable, and economically feasible.

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