Abstract

Nanomaterials (1–100nm in diameter) are leading in the rapidly evolving field of nanotechnology, due to their unique size-dependent properties like manifold surface chemistries, distinctive magnetic and electronic properties, along with tunable absorption and emission. Nanoparticles (NPs) with dimensions commensurate with biological functional units can act as acquiescent tools in diagnostic tests for prompt detection of diseases, for noninvasive imaging and drug development, and as a carrier for targeted drug delivery systems to lessen the harmful side effects of conventional drugs. Presently, 9.6 million people all over the world are infected with tuberculosis. Commonly used antibiotics like isoniazid and rifampicin have many side effects. To overcome this problem, the development of biocompatible, TB drug-coated nanomaterial/NP complexes involving Fe2O3 will be discussed with special reference to work carried out in our laboratories. The distinctive advantages of this system over treatment of TB with neat antibiotics will be highlighted.

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