Abstract
Publisher Summary This chapter discusses the reinnervation of skin by polymodal nociceptors in rats. Evidence indicates that the large group of sensory receptors in skin is the polymodal nociceptors, a group of receptors that have unmyelinated axons and which respond to a variety of intense and potentially damaging stimuli. Their large numbers imply that they are a particularly important group of sensory nerve fibres. Most would accept that impulse traffic in them is usually linked with pain sensations in man and with behaviour indicative of discomfort in animals. The technique of antidromic nerve stimulation and plasma extravasation is based on the observation that activation of unmyelinated axons results in an increased vascular permeability in the immediate neighborhood of the activated axons. Antidromic stimulation using the parameters mentioned in the chapter produced small areas of extravasation at sites that matched the receptive fields of the units.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call