Abstract
The future of biomedicine holds for new approaches and innovative therapies to face the main challenges and demands, currently, arising worldwide. This includes the diagnostic and/or treatment of innumerous severe and deadly diseases and pathologies that affect humankind. In this sense, the deep exploitation of the roles and assets of biological macromolecules, as well as the development of novel and targeted delivery systems for biomedical applications, become imperative. Following this, new therapies focused on targeting specific cellular organelles promoting gene expression, followed by protein production, and aiming restoring its normal functioning may constitute a valuable strategy for the treatment of neurological pathologies, diabetes, and cancer. Additionally, the combination of nanotechnology with chronobiology to adjust drug and or gene delivery according to each patient’s individual circadian rhythm emerges as an unique and original perspective in biomedicine, providing a step ahead on personalized cancer chronotherapy.
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