Abstract
The U.S. Food and Drug Administration (FDA) defines a drug as a substance, other than food or device, intended to affect structure or function in a human or animal. A variety of drugs are used to treat the different types of alopecia. Despite the high prevalence of hair loss and its social and economic impact, only androgenetic alopecia has FDA-approved drugs for its management: minoxidil for women and minoxidil and finasteride for men. At this point, all other therapies for the various types of alopecia are used off-label. This fact highlights the unmet need for well-designed clinical trials in alopecia that would ultimately lead to approved treatments. There is also an urgent need for discovery of new molecules to treat hair loss.
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