Abstract
Nanotechnology involves the development of potential applications such as engineered nanovehicles derived from nonpathogenic plant viruses and bacteriophages for drug packaging and payload delivery. Such plant virus-based engineered nanovehicles (PVENVs) are more advantageous compared with synthetic nanoparticles because of their biocompatibility and biodegradability. The viral coat protein in conjugation with small organic molecules or short peptides provides binder molecules that bind proteins with high affinity, selectivity, and prolonged half-life. PVENVs have been developed using several plant viruses, such as cowpea chlorotic mottle virus, potato virus X, cowpea mosaic virus, tobacco mosaic virus, and Brome mosaic virus; these plant viruses are widely used to engineer nanomaterials conjugated with a wide range of biocompatible molecules. This review focuses on the potential of PVENVs having vast applications in the medical field and agricultural sector, thus employing a renewable and environmentally safe method for producing PVENVs.
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