Abstract

The cerebellum is the primary center of motor coordination and is essential for sensory integration and higher cognitive processing. The cerebellum is an ideal model for the study of neurogenesis as it contains relatively few classes of neurons, each of which is located in a distinct lamina of the cerebellum, has a stereotypic morphology, and is characterized by the expression of well-defined cell-type specific markers. This chapter describes the recent progress in our understanding of cellular and molecular mechanisms driving cerebellar neurogenesis, which has been derived from the analysis of a variety of model organisms using powerful molecular tools.

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