Abstract
Oxidative stress arises due to an imbalance between the systemic expression of reactive oxygen species (ROS) and a biological system’s capacity to promptly detoxify the receptive intermediates or to fix the subsequent damage. Disturbances of the normal biological state might be associated with the pathophysiology of various disorders such as Alzheimer’s disease, Parkinson’s disease, diabetes, cardiovascular diseases (i.e., atherosclerosis, myocardial infarction, heart failure, etc.,), autism, etc. There are two types of antioxidant systems that compensate for the deleterious effects of oxidants, namely (1) endogenous antioxidants, which include superoxide dismutases, catalase, glutathione peroxidase, glutathione, alpha-lipoic acid, etc., and (2) exogenous antioxidants, which include vitamin E and C, plant phenols, flavonoids, etc. Epigallocatechin gallate (EGCG) is a well-known dietary antioxidant found in green tea and is reported to be effective against various cardiovascular, neurological, metabolic, and age-related disorders. This chapter starts with an introduction to oxidative stress from ROS to antioxidant systems. Further, this chapter discusses the protective role of EGCG, a dietary antioxidant, in the treatment of cardiovascular disease (atherosclerosis, cardiac hypertrophy, heart failure, and myocardial infarction), metabolic syndromes (diabetes and obesity), neurodegenerative disease (Parkinson’s disease, Alzheimer’s disease), aging, and cancer.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call