Abstract
The drug discovery and development process is advancing with time and in-silico research has enabled the identification of new drugs through target identification and validation. In-silico screening, quantitative structure-activity relationship, and quantitative structure–property relationship models are some techniques used to evaluate potential compounds with drug-like properties. The process of discovering new drugs is a time-consuming process spanning many years of hard work and resources. This chapter is an introductory chapter that provides information on recent trends in drug discovery in the post-genomic era. It discusses drug-discovery approaches using computational methods for target identification, validation, and homology modeling.
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