Abstract
The objective of this chapter is to analyze the transient temperature distribution in skin tissues due to short pulse laser irradiation. COMSOL Multiphysics, a finite element solver, is used to analyze the heat affected zone in a multilayer tissue geometry modeled by considering the embedded vasculature to account for the blood flow. Compared to the existing continuum model, the results predicted by the embedded vasculature simulations are in good agreement with the experimental temperature distribution measurements for experiments on live anesthetized mice. A parametric study has been performed to analyze the effects of varying blood flow velocities on the temperature distribution in tissues. Inclusion of embedded vascularity played a significant role in the analysis of short pulse laser-based therapy of soft tissues.
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