Abstract

There are a range of different potential points of origin for microorganisms in the processing environment and different vectors for transmission. These include people, air, water, and machinery. Within these broad grouping there are other areas. The risk posed by such microorganisms is ever present with sterile products; with nonsterile products a risk framework needs to be constructed. In all cases, where contamination is prevalent a remediation strategy is required, centered on repairs and cleaning and disinfection. The origins, vectors for transfer, and some suitable control strategies are discussed in this chapter.

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