Abstract
Means for the critical assessment of pathophysiological theories are offered. These are based on logical inconsistency and logical incompleteness. Logical inconsistency arises when the necessary axioms, taken as biological observations, and rules of inference, the manner in which the biological observations are integrated into a theory, are in conflict. Logical incompleteness is when there are statements that are taken as true yet cannot be explicated in the axioms and rules of inference of the theory. There are a number of phenomena that are evidentiarily true yet cannot be explicated by current theories or for which current theories are inconsistent. This includes the relation between bradykinesia and tremor, the variety of different pathophysiologies responding to the same Deep Brain Stimulation, latencies to Deep Brain Stimulation effects, and kinesia paradoxica. Theories based on nonlinear dynamics can explicate these findings demonstrates the potential power of this approach. These include hysteresis and self-organizing behaviors.
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