Abstract
This chapter presents the application of biomacromolecules as vehicles for successful encapsulation, release, and delivery of growth factors targeted for treatment in bone injury and bone regeneration. Additionally, it demonstrates how new formulations of growth factors by the aid of natural polymers can be synthesized using the experience and knowledge of the field of nano-drug delivery. The chapter starts with a description of the process of bone tissue regeneration in heal injuries and arthritic conditions and introduces the main ideas through the scope of allogenous and autogenous transplantation and describes the role of growth factors in these processes. In the next sections, special categories that are important in current growth factor delivery for applications in bone regeneration are presented. Examples include hydrogels, nanoparticles, and polysaccharide complexes in order to illustrate the methodologies for the investigation of loading and release of growth factors and characterization of the carrier systems at the nanolevel.
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