Abstract
This chapter discusses the antigenic analysis of Cryptosporidium parvum isolates of human and animal origin. Cryptosporidium parvum is a coccidian parasite that exists as at least two major genotypes: genotype 1 infects humans, and genotype 2 infects both human and other mammalian hosts. Genotypic variants may express phenotypic differences manifest in the composition and the assembly of the outer oocyst wall. Variation in outer oocyst wall composition may affect the interaction of the parasite with its environments, including interactions with the host and susceptibility to degradation as well as disinfection in water. This chapter presents a study which investigates the antigenic profiles of extracts from the outer oocyst wall of C. parvum isolates of both human and animal origin to determine whether such antigenic variation exists. Identification of phenotypic variants could assist epidemiology, prove useful for the further study of host parasite interactions, and it could be useful markers for developing new diagnostic methods and treatments.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
