Abstract
Osteoporosis is a degenerative disease with the porous bone condition, severe loss of bone density takes place due to the low calcium intake as well as aging. This leads to a high risk of fractures along with hormonal imbalance. The main drawbacks of the existing conventional therapies are their adverse side effects with some pharmacological concerns. Thus, upcoming studies should be focused on advanced treatment on inducing tissue regeneration with more efficacies. Nowadays, nanoparticles-based tissue regeneration has become a popular alternative for osteoporosis treatment due to its high efficiency. Nanoparticles bring an impact in recent days and serve as potential drug delivery to treat bone diseases. Recent studies have shown that nanoparticles like gold, silica, platinum, silver, cerium are commonly used for carriers as drug delivery together with growth factors for bone and tissue regeneration, bone grafting. Nanoparticles provide mechanical strength and allow tissue regeneration. Further, these nanoparticles induce osteoblast and osteoclast lineage when compared to conventional treatments. This chapter summarizes the applications of nanoparticles, recent advances, limitations, and their impact on the treatment of osteoporosis.
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