Abstract
Diagnosis and effective therapy of microbial infections are often complicated processes. Antibodies can be used for rapid, specific diagnosis and therapy of those infections because of target selectivity and specificity. Monoclonal antibodies show higher target specificity compared to polyclonal antibodies. Single epitopes specificity of monoclonal antibodies makes them the leading therapeutic and diagnostic tool against microbial infections by lowering the potential of off-target reactions and misleading diagnosis. Employing monoclonal antibodies to diagnose and treat microbial infections has been attracting significant attention despite some economic obstacles. This chapter focuses on the potential diagnostic and therapeutic use of monoclonal antibodies to combat different microbial infections, including bacterial infections, viral infections, and some other infections in vivo and in vitro. The recent advances made in monoclonal antibody development against various microbial diseases for diagnostic and therapeutic purposes are discussed. Finally, some key challenges in designing, manufacturing, and developing monoclonal antibodies for diagnostic and therapeutic systems and their limitations and future trends are explained.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
