Abstract
The application of biocatalysts to the synthesis of active pharmaceutical ingredients (APIs) has grown rapidly in the recent years. This review provides examples on the application of isolated enzymes (wild-type or mutants) and whole cells, either in soluble or immobilized form, for the synthesis of some valuable APIs, at both industrial and laboratory scale. The biocatalytic productions of enzyme inhibitors with therapeutic effect, drugs that modify the transport across membranes and drugs that interact with membrane and intracellular receptors are reviewed.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
