Abstract
In this chapter, we begin the discussion of how computational methods can be used to study various biofluid mechanics problems. We start by presenting various computational methods, such as the large eddy simulations and direct numerical simulations. The use of various computational programs is illustrated with a rapidly expanding channel and then the human left main coronary artery. We then move into a discussion of the need for and the difficulty of fluid structure interaction modeling, in which the movement of blood vessels can be coupled to the fluid flow through the blood vessel. Particle trajectories and the calculation of the shear history on particles are presented. The development of the Buckingham Pi Theorem is discussed, to derive salient dimensionless numbers. Some of the important dimensionless numbers for biofluid mechanics are presented. These numbers can be used to develop dynamically similar conditions.
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