Abstract
Analytical chromatographic methods are widely used for the analysis of organic compounds in different matrices. Traditional gas and liquid chromatographic methods are characterized by large consumption of resources and waste generation leading to harmful impacts on operators’ safety and on the environment. With the scientific and public awareness about the environment and human health, analytical community members have been motivated to use green alternatives and replace polluting analytical methodologies with clean ones. In this context, implementing the principles of green analytical chemistry in analytical laboratories is highly desired. Liquid chromatography could be greener by using more eco-friendly solvents, reducing the solvent volume needed by using shorter and/or smaller diameter columns packed with fully porous sub-2-μm particles or superficially porous particles, and high temperature mobile phases.
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