Chapter 14 - Supercritical solvent-assisted green isolation of naturally occurring therapeutically active nanomaterial—a review

Abstract

Recent advancement in isolation techniques of therapeutically active natural nanomaterial focuses on the utilization of supercritical solvents as a greener approach. In conventional methods, the solvents utilized were either having higher e-factors or act as environmental pollutants. Another potential hazard of conventional solvents was their carcinogenicity and different physiological hazards. Chemically conventional solvents had less atom economy. Economically conventional solvents were having higher procurement costs. With utilization of supercritical solvents (supercritical CO2, supercritical H2O, and other) for isolation of nanomaterial, the adverse environmental impact can be reduced, economic viability can be ensured, physiological hazards can be reduced, sustainable development Goal-2030, Goal-3: Good health and well-being, Goal-12: Responsible consumption and Production can be achieved.