Abstract
The two major systems responsible for body control and communication are the neurological system and the endocrine system. The endocrine organs release hormones, which travel through the body and control a range of responses including fertility, growth, and development. Certain chemicals have been implicated as endocrine disruptors and the potential endocrine-disrupting effects of nanomaterials have also attracted increasing attention. Since adverse effects on the endocrine system may influence a wide range of physiological processes, it is imperative to systematically assess these endocrine toxicities of nanomaterials. The present chapter provides an overview of the known effects of nanomaterials on different endocrine organs in the body, and the possible underlying mechanisms are also highlighted. The discussion of nanotoxicity is necessarily extended to other aspects of toxicity of nanomaterials, including genotoxicity and cytotoxicity, as well as ecotoxicity, where relevant.
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