Chapter 14 - Dietary Quercetin and other Polyphenols: Attenuation of Obesity

Abstract

Obesity is a high-risk factor for the development of metabolic syndrome that increases the risk of cardiovascular diseases. Vegetables, fruits, and tea are considered to reduce the risk of cardiovascular disease. Tea catechins have been shown to increase energy expenditure and fat oxidation and reduce body weight in randomized control studies. Caffeine intake and ethnicity may influence the effects of catechins. Quercetin is the most common flavonoid in vegetables, fruits, and tea. Animal studies suggest that chronic intake of dietary quercetin attenuates obesity and metabolic syndrome, mainly by suppressing increased oxidative stress and related inflammation. Resveratrol in wine may improve insulin resistance and obesity by increasing the mitochondrial function. The attenuating effects of polyphenols on obesity are relatively low; however, habitual intake of polyphenols from dietary sources may help to promote health and prevent or attenuate obesity and metabolic syndrome.