Abstract
The chapter largely focuses on the application quality by design (QbD) on self-emulsifying drug delivery system (SEDDS). SEDDS, an isotropic mixture of lipid, surfactant, cosurfactant, and drug, is a promising technology to improve the bioavailability of poorly water-soluble drugs. The chapter is primarily sectioned into (a) application of Box-Behnken design in SEDDS, (b) application of central-composite design in SEDDS, (c) application of D-optimal design in SEDDS (d) application of full-factorial design in SEDD, and (e) application of simplex-lattice design in SEDDS, followed by an exhaustive table illustrating the application of QbD in SEDDS. The literature reviews on QbD on SEDDS unequivocally exemplify the wide acceptance of application of the statistical tool in the development of SEDDS.
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