Abstract
Traditional diagnostic testing for male infertility has been known to lack precision for some time. While some important findings can be yielded from the typical semen analysis, the findings rarely change the course of care for most couples. The ability to analyze the male factors that directly predict the likelihood of a successful pregnancy with various clinical interventions would drastically improve the state of diagnostic testing in male fertility. Because both inherited and environmental factors have been linked to fertility, epigenetics has the potential to be informative both about etiologies of infertility, but most importantly could be a key to the prediction of successful pregnancies and the utility of various treatments. The use of epigenetic testing could improve the precision with which a diagnosis of male infertility could be given.
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