Abstract
CyberInfrastructures (CIs) are complex socio-technical-economical systems that are difficult to describe, design, analyze, and evaluate. As one example, E-Health CIs are patient-centric community-serving systems that have particular regulations for information security, governance, resource management, scalability, and maintainability. We have built multiple successful E-Health interdisciplinary projects at the University of California, San Diego, including CYberinfrastructure for COmparative effectiveness REsearch (CYCORE) for cancer clinical trials, Personal Activity Location Measurement System (PALMS) for studying human activity patterns, CitiSense for sensing city pollution, and Integrating Data for Analysis, Anonymization, and SHaring (iDASH), which is a National Center for Biomedical Computing. These CIs have served their user communities well with respect to their projects’ goals and durations. Due to their shared requirements, these systems were all designed around the service bus-based Rich Services software architecture. However, there are also significant differences in how these CIs were designed and implemented, which might be informative to the community of CI developers.
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