Abstract

A great number of currently available synthetic polymers makes the selection of a suitable polymer for a particular biomedical application a difficult task. However, among all properties required for an application, the biocompatibility of the polymer with tissues and biological fluids is always the foremost consideration for all candidate materials. Here, cellular response of the synthetic polymers has been discussed in direct correlation with their biomedical applications, such as implants (joints, sutures, bone plates), and medical devices such as blood tubes, artificial heart, pacemakers, etc. They are classified in inert and degradable ones and in each class the factors related to polymer characteristics and biological media determining biocompatibility and cellular response have been evidenced.

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