Chapter 12 - Biomedical application of supramolecular coordination complexes

Abstract

Metal complexes have been widely used in medicine. Starting from anticancer drug cisplatin, a lot of different transition metal complexes have been developed to date to act as potential anticancer agents. The platinum, palladium, and ruthenium complexes have got much attention due to their efficiency in treating cancer cells. Apart from the simple mononuclear complexes like cisplatin large supramolecular complexes have also been used for the antiproliferative activity. The supramolecular coordination complexes which can be easily designed and synthesized via a self-assembly approach are of present focus for biomedical application. Some of the supramolecular coordination complexes have been also used as cargo for efficient drug delivery to target cells. In this chapter, the prominent coordination-based supramolecular complexes for their biological application have been discussed.