Abstract
The cardiovascular functionality is dependent on age, which deteriorates in older adults making them susceptible to Cardiovascular Diseases (CVD). The accumulation of elderly in population imposes effective strategies to reduce or manage CVD. To mitigate the deleterious effects of aging and maintain a youthful cardiac phenotype, several therapeutic approaches aim to augment or retain the cardiac reparative potential by antagonizing cardiac cellular senescence. The myocardial and nonmyocytes cells show reduced replicative potential and dysregulated cellular processes in an aging organism, remains a target for research to enhance cardiac repair. Impairment of angiogenesis is strongly associated with aging, resulting in cardiac remodeling, heart failure and cardiovascular death. Cardiac stem cells such as CDCs and CASCs promote the angiogenic process for optimal heart function. Therapeutic angiogenesis using cardiac progenitor cells could serve as an intervention to stop the accelerating cardiac aging after gathering evidences though clinical studies.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
