Abstract
The development of electrochemical sensors is one of the most active areas of analytical research in many fields, including clinical and environmental analysis. Potentiometric sensors are devices that incorporate a recognition element with a signal transducer and monitor the voltage at zero current. Over the past two decades, imprinted polymers have attracted broad interest from scientists appointed in electrochemical sensor development. The possibility of tailor-made, highly selective artificial receptors makes these synthetic materials ideal recognition elements in electrochemical sensors. This chapter introduces molecularly imprinted polymer-based potentiometric sensors and offers a survey of the principles, fabrication, and biomedical applications of electrochemical devices in the determination of drugs in pharmaceuticals, biological fluids, and environmental samples. These electrodes are usually validated with respect to parameters, including linearity, limit of detection, sensitivity, selectivity, reproducibility, accuracy, robustness, response time, and lifetime.
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