Abstract
Cardiovascular diseases (CVDs) are the world’s leading cause of death. Risk factors that promote CVDs are often associated with human lifestyle choices such as unhealthy diet, sedentarism, tobacco and alcohol consumption, hypertension, hyperglycemia, and hypercholesterolemia. The CVDs have significative socio-economic burden that makes it even more important to find new ways to reduce its incidence and to better treat the ones already suffering from it. Lately the pharmaceutical industry is turning the attention to products of natural origins and in their potential uses as treatments for several conditions. Phenolic acids are one of the main types of phenolic compounds that have been finds in several plants and vegetables. Studies show that phenolic acids have biological activities related with the prevention of CVDs. In this chapter we review the recent evidence on the role of phenolic acids and their derivatives in the treatment of CVDs, and mechanisms of action in the pathophysiology of CVDs.
Published Version
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