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Abstract
Gout is the most common form of adult inflammatory arthritis and is caused by the persistent elevation of serum urate above its solubility concentration. Gouty flares are characterized by the abrupt onset of excruciating pain in one or more peripheral joints that self-remit over a week or more. The other clinical characteristics of gout typically appear after a decade of intermittent symptoms and include the appearance of clinically-apparent tophi and persistent joint symptoms. Women who develop gout usually have the onset of symptoms a decade or two later than men. The pattern of joint involvement also differs between men and women. Both early and advanced gout have a significant impact of patients’ quality of life.
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