Abstract

The aim of this book is to present biochemical, functional and relevant biological information about the proteins of the complement system. This edition of The Complement FactsBook contains updated information for all sections of the chapters in the first edition, particularly with respect to the structural domains and, where available, the crystal structure of the proteins. In addition, this edition covers information on complement mutant mice including their generation and disease phenotypes. Since the publication of the first edition of this book, many new complement proteins have been characterised and these proteins are now included in this edition.

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