Abstract
In this chapter we discuss interactions between colloidal particles in an electrolyte solution such as drug particles of colloidal dimensions (nanometres to micrometres) and biological cells on the basis of the Derjaguin–Landau–Verwey–Overbeek theory of colloid stability. This theory assumes that two fundamental interactions are acting between two approaching colloidal particles, that is, the electrostatic repulsive interaction due to overlapping of the electrical double layers surrounding the particles and the van der Waals attractive interaction and that the balance of these two interactions determines the stability of a suspension of colloidal particles. We treat not only hard particles without surface structures but also soft particles, i.e., polyelectrolyte-coated particles, which serve as a model for biological cells.
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