Abstract

This chapter describes the basic physical properties of proteins and nucleic acids and the basic definitions and concepts involved in the study of macromolecular chemistry. It concentrates on the physical foundations of experiments to present a largely nonmathematical picture of the physical chemistry of macromolecules. The chapter elucidates properties such as mass, shape and structure, and color along with kinetic, electric, and magnetic properties. In particular, the chapter highlights the differences in the properties of small molecules and macromolecules and relates biophysical properties to biological function. The chapter also explains the concept of Fourier transform—a pervasive and useful tool in the physical sciences. Fourier transforms are definite physical operations that analyze a periodic function.

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