Abstract
Some potential clinical applications of hyperbaric oxygenation have been reviewed. The strong influence of several physiologic processes on oxygen transfer and distribution limit the application of this modality, but several definite indications for its applications have developed. Hyperbaric oxygen is definitely useful in carbon monoxide intoxication, gas gangrene and compression sickness. Some reduction in operative mortality has been achieved in surgery for congenital heart disease in infants. It has also apparently helped resuscitation of some heart patients with low output syndrome and intact coronary circulations. It has facilitated recovery of some partially ischemic limbs, especially those with surface infections that were causing or promoting local gangrene. The individual chambers, despite their limitations, offer a good method for fulfilling medical indications for hyperbaric oxygen.
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