Abstract
The results reported in this study demonstrate that the amount of calcium excreted into the urine postprandially is a reflection of calcitonin (CT) activity during the feeding process. Comparisons were made among normal rats, rats with intact thyroids and functional parathyroid transplants (TI), and thyroidectomized rats (maintained on T4) with functional parathyroid transplants (TX). CT replacement was provided by hormone injection at both 30 min and 2 h after the onset of feeding. A 4-h urine collection was made, commencing 2 h after providing the rats with their daily allowance of food. Postprandial urinary calcium values were determined on the day rats were transferred from a calcium-containing diet to a calciumfree diet. CT was only administered on days the rats received the calcium-containing diet. The following results were obtained. In rats maintained on a constant calcium-containing diet, postprandial urinary calcium values were lower in TI than in TX rats. The reverse was true for the first day ...
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