Changes induced in cell membranes adsorbing animal viruses, bacteriophages, and colicins.

Abstract

Binding of various ligands (hormones, neurotransmitters, immunological stimuli) to membrane receptors induces the following changes: 1. Receptor redistribution (cluste ring, “capping”) 2. Conformational changes that can be detected by fluorescent probes 3. Alteration in membrane fluidity (spin label and fluorescence polarization probes) 4. Changes in fluxes of ions and metabolites 5. Increased phospholipid turnover (especially of phosphatidyl inositol) 6. Activation ofmembrane-bound enzymes (adenyl cyclase, ATPase, transmethylases). KeywordsInfluenza VirusNewcastle Disease VirusVesicular Stomatitis VirusDiphtheria ToxinSendai VirusThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.