Abstract
The article presents data about the use of NADP against streptozotocin-induced diabetes mellitus in rats. It has been shown that in the early period of the development of the experimental diabetes mellitus, changes in the basal membrane of the glomerular capillaries, mesangial matrix and mesangial cells, as well as the basement membrane of the Bowman capsule, occur during the 11-31 day in the renal cortical substance. Administration of NADP to the experimental rats at a dose of 30 mg/kg of body weight resulted in a partial improvement of the condition of the mentioned renal structures.
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