Abstract
An attempt was made to employ the oncolytic reaction to evaluate the efficacy of sarcolysin treatment in Guerin's rat carcinoma. The oncolytic properties of the sera were periodically investigated in rats suffering from this tumor and treated with sarcolysin. The results obtained were compared with the changes in the oncolytic properties of the serum of animals with tumors untreated with this perparation. It was demonstrated that the rise of the serum oncolytic activity in the treated animals is associated with the reduction of the tumor size. Conversely, the activity fall in the serum oncolytic activity in rats suffering from tumors not treated with sarcolysin is associated with the continuous growth of the tumor. It appears that determination of the oncological properties of the serum during sarcolysin treatment of animals suffering from tumors would enable the efficacy of this therapy on the tumor to be evaluated.
Published Version
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